Psychotic Cannabis Withdrawal: A Clinical Case

Zweevteev

Wijs gebruiker
Dit is een onderzoek dat gepubliceerd is op 13 november 2022, gaande over cannabis-geïnduceerde psychoses, in het bijzonder psychoses die aangewakkerd worden door abrupt gestopt/significant gereduceerd gebruik. Het is niet een heel lang onderzoek en is best makkelijk in één keer door te lezen, dus voor de mensen die het interessant vinden, hier kan je het volledige onderzoek vinden: https://www.cureus.com/articles/124016-psychotic-cannabis-withdrawal-a-clinical-case

Psychotic Cannabis Withdrawal: A Clinical Case​

Berta Ramos, Ana Filipa Santos Martins, Eva Sofia Lima Osório

Abstract​

Cannabis use has been associated with several psychiatric comorbidities and there appears to be a dose-response relationship between the intensity and duration of its use and the risk of psychosis. More commonly, acute episodes of cannabis induced-psychosis manifest immediately following exposure, are precipitated after the use of large amounts of cannabis, resolve with abstinence, and are of shorter duration than those observed with primary psychotic disorders.

Cannabis withdrawal symptoms usually manifest when heavy, prolonged consumption of this substance is interrupted or significantly reduced. The withdrawal syndrome may include sympathetic autonomic hyperactivity, irritability, anxiety, sleep disturbance, and reduced appetite. On the other hand, cases of psychosis induced by cannabis withdrawal are rare.

In this case, we present a 32-year-old healthy woman without personal or family psychiatric history who showed a heavy and continued consumption of cannabis since she was 10 years old, without developing any psychiatric symptoms. However, recently she experienced two brief psychotic episodes with disorganized behavior and persecutory delusions, both episodes happening a week after discontinuing cannabis consumption.


Introduction​

Cannabis use has been associated with several psychiatric comorbidities, including mood, anxiety, and psychotic disorders, particularly in the case of consumption at an early age [1]. While these associations are well established, the mechanisms involved are not fully understood, with inconsistent and even contradictory findings [2].

Cannabis withdrawal syndrome occurs when heavy and prolonged consumption of this substance is interrupted or significantly reduced. Its symptoms usually appear within 24 to 72 hours and last for about one to two weeks [3]. It can mimic withdrawal syndromes from other substances, such as alcohol or opioids, with sympathetic autonomic hyperactivity, stomach pain, tremors, sweating, fever, headaches, irritability, anxiety, sleep disturbance, and, more rarely, psychosis [4-6].

In addition to the cannabis withdrawal syndrome, the Eleventh Revision of the International Classification of Diseases (ICD-11) includes cannabis-induced psychotic disorder, which is characterized by “psychotic symptoms that develop during or soon after intoxication with or withdrawal from cannabis” and that “are not better explained by a primary disorder” [7]. While intoxication-induced psychotic cases are commonly described on literature, psychotic cases after cannabis cessation are rarely reported.
 

LucidLucy

Verslaafde in herstel
Hmmm bijzondere case. Wel interessant report. Heel lastig om nou precies de vinger te leggen op wat zon psychotische episode nou precies veroorzaakt. Slaaptekort wordt als een van de mogelijk meespelende factoren genoemd.

Heel vaak gaat wietgebruik gewoon goed. Maar zo af en toe lijkt het net russisch roulette.
Zeker als je leest dat de persoon in kwestie geen psychiatrische geschiedenis had en ook familiair niet.
 
Bovenaan